My brother in law has this and so does his sister. I know that their parents (my in laws) are carriers of this but no one else,that we know of,has had this.How did my in laws become carriers?

Your in laws became carriers through random chance of abnormal genes passed on through their genetics. It is absolutely nothing that they physically did. It is a rare genetic disorder and therefore passes through families. Do you brother and sister in law have the disease or are they carriers as well? Since your in laws are only carriers, they should not express the disease, but since two carriers happened to find each and have children, their children have a chance of either being fine, being a carrier, or having the disease. Again, it is rare, which is why you probably do not know of anyone else with the disease. Someone can be a carrier, but unless they have children with another carrier and produce a child with the genetic disposition for the disease, they may never know that they are a carrier. It is a strange twist of luck that both of your in laws carried the abnormal gene.

Which is cheaper fredericks of hollywood or victorias secret?

Im doing a photoshoot and need 3 sexy outfits (bra and pantie type things) no print nothing too stripperish. bedrrom abd bathtub scenes will be done.

It depends what you are looking for. Slut clothes go to Freds and over priced but comfortable bra and panties go to Vickys. You pay for what you get. Check out the clearance section on line.

My husbands brother has it and i dont really understand what it is or if it gets worse with age or is in the family genese if anybody knows pls tell me.thanks.
see i would have asked my mother and father in law but they died when he was 4 so i cant.could our children have it? My husbands brother has it and i dont really understand what it is or if it gets worse with age or is in the family genese if anybody knows pls tell me.thanks.
see i would have asked my mother and father in law but they died when he was 4 so i cant.could our children have it?

I believe you are referring to Friedreich ataxia. This a rare genetic disorder that affects the nervous system. Yes, it is progressive. It's an abnormality of sensory and motor nerve conduction and primarily involves the spinal cord. The main symptoms include progressive ataxia (uncoordinated movement of the limbs), dysarthria (difficulty speaking), nystagmus (jerky movement of the eye muscles), a decrease in reflexes, disease of the heart muscle and scoliosis. The symptoms start in middle childhood and most are wheelchair bound by 43-46 years of age. Some of those affected may live into their 70s provided there are no complicaitons from heart disease or diabetes. So far, there's no proven therapy to reverse or lessen the neurological changes.

Your mother- and father-in-law both carry the gene (frataxin mitochondrial protein) that causes this. They are not affected because they each have only one abnormal gene and it takes two abnormal genes to result in Friedreich ataxia.

Can you determine if a child is going to have fredericks ataxia before the child is born?

I have a friend who is 6 months pregnant and the father was diagnosed with it in his early 30's. his father and aunt passed away from it. he was never diagnosed until his early 30's.is there a screening that can detect it either while the mother is pregnant or when the child is a baby? and what are the chances of the child getting this.

They can do an amnio test, but they are dangerous. They basically stick a giant needle in the belly of the prego woman, through the sac and take a sample of the fluid. The chance of miscarriage afterwards is high. Your friend will need to discuss the pros and cons of the procedure with a doctor and the baby's father.

Even if the test is performed, will it change the outcome of the birth? While a negative result would calm the nerves a bit, what would a positive result do?

I just read the first book of the In the Cards series!
I really liked it, It was a little weird but its a good book!

Fredericks's young characters are given a deck of tarot cards when an old woman dies in Anna's apartment building. This sets up the dilemma about whether our lives are preordained, or whether we have free will. As usual, Fredericks writes about intelligent, thoughtful adolescents. It's not all heavy philosophizing, that's for sure. There are cats involved in the story, and friendships, little brothers, and fights at school and a misfit. As always, Fredericks knows her audience well and entertains them."
-K

Does anyone know how much of an employee discount you get working at Victoria Secret & Fredericks ?

And what you get paid an hour ?

I applied at Victoria's Secret a month ago and they offered me a job with a 30% discount and they were going to pay me $7.10 but they said that they usually pay people less than that. I turned it down, that's just not enough money!

When does the Fredericks of Hollywood End of Season sale end?

Does anybody know?

Try going to their website:
http://www.fredericks.com

or go to this link:
http://www.fredericks.com/category.asp? ... me=On+Sale

Who else loves shopping at Fredericks of Hollywood?

I love this store.

As a sissy i love Fredericks, the girls at my local shop LOVE to play dress up with me and make me try on outfits! i go there every 1st and 3rd wednesday when they open so they can humiliate me and dress me up!