Ssri Side Effects

Why do SSRI drugs cause side effects ?

New postby Jamal » 29 Oct 2012, 08:37

Why do SSRI drugs cause side effects ?

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New postby Bette » 29 Oct 2012, 08:37

When you are tweaking chemicals in your brain there are going to be different reactions. Not everyone has the same reactions or to the same extent. MOST side effects lesson and go away withing a few days, though some you will experience for the entire time you are on the medication.

For this reason it may take some time to find the right medication and the right dosage for each person. The question we must ask ourselves the side effect worse than the problem for which we are taking the medication, i.e., is a bit of initial dizziness worse than ongoing panic attacks.

Many medications cause side effects and certainly the SSRI's are not the only ones. Antipsychotics, anti-cholesterol, heart meds, asthma drugs...all have side effects.

Again, you cannot tweak the brain or body with drugs and no expect to have some side effects. Only you and your doctor can make the decision as to whether or not the need for the medication outweights the side effects.
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Gingko biloba against SSRI side effect?

New postby Allena » 29 Oct 2012, 08:37

This was posted in alternative medicine group but the people were ridiculously callous and rude. I am taking Zoloft for panic disorder and experience sexual side effects from it (I am female). I read promising things on the web about gingko being used to counteract this. Does anyone have personal experience and can recommend a certain brand or any other POSITIVE info about this topic? NOTE: I am looking for help, NOT criticism or your personal opinions about my condition (I see a doctor regularly and have spoken with her about this, by the way). If you are going to spout off about how drugs are bad or condemn me for something, keep your "answers" to yourself.
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New postby Flo » 29 Oct 2012, 08:37

I afraid this really isn't going to be much of an answer, but I am currently reading alot about gingko biloba for the same reasons. My boyfriend is on Effexor and it has almost entirely wiped out his sex drive, right down to the point where we barely kiss. For a long time, he didn't let me know what was causing this and I took it very personal. I thought there was something wrong with me, and/or that his feelings had changed. My advice to you if you are in a relationship, is to be open and honest about your condition with your partner. From someone who is on the other side of this issue, it can be very confusing and depressing. I feel for you totally and hope that we all can find something to help. It's difficult because the Effexor is working very well for him in all other ways...yet I think it's gotten to the point to where he doesn't FEEL much of anything. Intimacy and romance simply don't exist for us anymore. I'd be curious to know if you are experiencing this to the same degree. When we do have sex, it's always wonderful, but it seems to be getting more and more difficult to plan, and the frequency is getting less and less. For us, it's going on 7 weeks. I have absolutely no way to initiate it, and have given up trying.
From what I've read about Gingko so far, there are a lot of conflicting reports. Some have sworn by it, others have completely dismissed it. I guess we'll just have to see for ourselves. The best of luck to you.
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SSRI with less side effects?

New postby Manie » 29 Oct 2012, 08:37

I had developed Depression along with Severe Anxiety.and its getting worst.thought i could handle it with Herbal meds but now i seem to cant function. and losing touch with who i used to be. I'm very desperate now. so i'm chosing to go on anti-depressants. I have Four different types Meds to choice from. and i'm asking you guys which has the least side effects. cuz i'm very scare to take this stuff. but its been three months of hell. feeling like i'm losing my mind .I'm scare because i think they will make me more crazy than what i am. and anxiety tends to make you scare of alot of things.
These are my choices of Meds that i have a prescription for
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New postby Adam » 29 Oct 2012, 08:37

Lexapro is actually related to Celexa. You can get Lexapro from Celexa. These are SSRIs.
Remeron (mirtazapine) is a unique drug. There is nothing else like it. This is not a SSRI.
Effexor is related to the more side effect prone tricyclic antidepressants. This is not a SSRI but a SNRI.
Theoretically, Lexapro shouldn't have that many side effects. However, side effects is dependent on the person. The side effects are fairly similar with these drugs.
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Stopping an SSRI, having crazy side effects, help pls?

New postby Setsuko » 29 Oct 2012, 08:37

I am planning on enlisting in the navy after this school semester and they want me off my medication (150mg zoloft) for 6 months. the recruiter said he could give me a break with 2-3 months off it so i stopped taking it. im getting crazy dizzy spells, vivid dreams with horrible night sweats and the dizzy spells radiate to my limbs in the form of a quick and temporary numbness. i want into the navy for specific reasons but need to get rid of these side effects. on a side note im also drowzy all the time an sleep more but these are minor compared to the other things i mentioned. is there any way to minimize the symptoms ive been having? and i also took my dosage down to 100 mg for a week before i quit completely.
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New postby Osvaldo » 29 Oct 2012, 08:37

You HAVE To taper down the dose... you are on 150 mg, cut that in 1/2 for a few days (5)....... take 1/2 in the morning & 1/2 at night... then go to 1/2 in the morning only...x 5 days ........ then take 1/2 every other morning x 5 days, then 1/2 every 3rd day for 5 days then you will be done.

You are having withdrawl symptoms from taking yourself off the medication to soon, that medication stores in your system & you can get sick by stopping it rapidly...
The only way to minimize the symptoms is to taper slowly...

Don't stop completely, you will withdrawl for about 10 days with no medication at all..
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What are the side effects of using Crystal meth while...

New postby Colette » 29 Oct 2012, 08:37

What are the side effects of using Crystal meth while taking an SSRI and or bi polor medication.?

First off I would just like to say I am a firm believer in not using drugs. This question is to further educate myself on the subject, because of history with family members and friends.

I have allot of people I know taking SSRI medication for depression, like Paxil; but they also take a medication used to treat bi polor disorder called lamictal, and another for paranoia( I don't what that one is called.) Anyways my question is, what happens if while they are taking those they bring Crystal meth into the mix?

What are some of the risks and side effects. If anyone can let me know as soon as possible I would really appriciate it.

Oh ps.
Don't do drugs not a good idea ^_^
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New postby Roosevelt » 29 Oct 2012, 08:37

Taking meth is a really bad idea for a bipolar patient. Even therapeutic doses of stimulants used to treat ADHD can increase mania in bipolar patients, and methamphetamine is a much stronger stimulant than those used to treat ADHD. It can sometimes induce mania even in users with no history of bipolar disorder, so it's definitely a bad idea for someone with bipolar disorder. It can also increase paranoia.

One of the papers I read for my psychopharmacology class today looked at compounds that increase the release of serotonin as a possible treatment for addiction to stimulants (cocaine and amphetamines). They found that in rats, these compounds seemed to decrease relaps into drug use, possibly because they decreased the "reward" effects of the drug (i.e. the "high" that people are looking for). SSRIs also increase the levels of synaptic serotonin, so they could potentially have that effect as well. So one possibility is that the person simply wouldn't get high (or as high) if he took meth while on an SSRI. That could be potentially dangerous if that individual increased is meth intake to try to achieve a high as this could lead to an overdose.

Another concern I have with mixing meth with an SSRI is that while meth has a significantly greater effect on dopamine that serotonin, it does increase the levels of serotonin as well. The mechanisms of action are sufficiently different that I think that the effects would simply build on each other, resulting in more serotonin. In combination with an SSRI, it could potentially result in too much serotonin, leading to a serious, and potentially fatal condition known as serotonin syndrome. Although serotonin syndrome is rare, and is more often associated with MAOIs than SSRIs, it's definitely a very real possibility as amphetamines are one of the street drugs that are associated with fatalities when taken with MAOIs. Several mood stabalizers are also associated with serotonin syndrome, so the lamictal could also increase that risk.

I'm not very familiar with the mechanisms of action of mood stablizers or antipsychotics (which could be used to treat paranoia), so I can't say much about the specific interactions that could occur with methamphetamine. I do know that many antipsychotics act on dopamine, which is also one of the main targets of meth, so there's the potential for an interaction there, but I'm not sure what that might actually do.

Another concern is that the medication used for the paranoia could potentially be a CNS depressant (despite the name, that's the opposite of a stimulant rather than an antidepressant). Mixing a stimulant with a CNS depressant can result in cardiac arrhythmia (irregular heartbeat), which is potentially fatal.

Overall, I'd say that mixing methamphetamine with the drugs and conditions that you listed falls into the catagory of "really bad ideas."
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Ginkgo biloba to counteract SSRI side effect?

New postby Klara » 29 Oct 2012, 08:37

Hi, I am taking Zoloft for panic disorder and have discovered the unpleasesant sexual side effects. I read promising things on the web about ginkgo and how many people have found it to be very helpful in this situation. Can anyone recommend a specific brand of ginkgo? I found the recommended dosage but it is a little hard to match everything up in one brand. Or if anyone has found any other positive ways to counteract this, I would appreciate hearing about it! Thanks!
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New postby Xuan » 29 Oct 2012, 08:37

First of all, I'm sorry to see the other answers have been a bit rude. Some people do need SSRIs, and they do have sexual side effects (lessened sensation being the most common).

Ginkgo, however, will not help you in this situation. It primarily benefits memory, concentration and mental focus in older individuals.

Before recommending a natural or herbal remedy to assist with your problem, it is important to know whether you have other medical conditions such as low thyroid, autoimmune disease, or high blood pressure. Certain herbs are contraindicated for those conditions, and certain herbs are contraindicated for individuals taking SSRIs.

If you do NOT have any of the above-listed medical conditions, some herbs that would be of benefit (if you are female) include Ashwagandha and Maca. If you are male and do NOT have any of the above-listed conditions, Yohimbe is also helpful.

I would strongly advise visiting a health food store and consulting with a *QUALIFIED* herbalist or nutritionist before you take any herbal remedy. Just because it's natural doesn't mean it's safe for YOU....herbs must be treated with the same respect as a prescription medication.

You may also want to consider topical applications that assist with arousal. There are many excellent natural brands; again, your health food store can best recommend one to suit you.
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Which ssri has the fewest side effects?

New postby Mark » 29 Oct 2012, 08:37

Which ssri has the fewest side effects?
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New postby Stepanie » 29 Oct 2012, 08:37

Loaded question. You will react differently than everyone else when taking an SSRI, you will need to discuss your history with a doctor and will probably end up going through a few till you find the one that works best and has the least side effects for YOU.
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Why does Zoloft (and other SSRI's) cause sexual side...

New postby Sue » 29 Oct 2012, 08:37

Why does Zoloft (and other SSRI's) cause sexual side effects? Are they easily reversible?

I've been prescribed Zoloft for OCD (the OCD is killing my lifestyle). I don't mind having a diminished libido while I'm on the drug, as I may only need to be on it for 6 months or so, but what scares me is this:

And other accounts of ongoing sexual side effects because of SSRI's with a large support community. Frankly, I don't want to be part of this community, especially because I'm a 22 year old male who hasn't even had sex yet. The angst would be unbearable if I lost something like this now, and yet, the OCD is becoming unbearable also.

My real question is, if I go on the drug, will the side effects most definitely reverse?

It would help to know why the hell it causes sexual side effects in all people, and why it doesn't reverse in some people as well. True statistics say that when people were asked the sexual side effects were more like 60-80%, the other 20-40% would have been so depressed and/or anxious to have even noticed. Thanks
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New postby Louise » 29 Oct 2012, 08:37

Not everyone who takes zoloft has sexual side effects, but many do and they run the gammut from mild difficutly with arousal and orgasm (for men and women) to complete inability to get an erection. For many, the milder side effects aren't a big problem, in fact, SSRIs are sometimes used in men with premature ejaculation to delay the response to help increase self and partner satisfaction.

If you do have a side effect which is not acceptable, it should go away when you stop the med, and you could try another SSRI to see if you can avoid it. Since SSRIs work by increasing serotonin in the synapses, and succesful sexuality requires a balance between serotonin and other neurotransmitters in the brainstem, problems with one SSRI may well mean problems with all. I have not seen or heard of a non-reversable sexual problem from zoloft and I have treated a large number of patients. I'm sure it has been reported, but I would question whether there is some other issue confusing this since there is no good reason it should have a lingering effect.

Finally, there are treatments for people who need to be on an SSRI but have sexual side effects. Several other meds taken regularly (like wellbutrin), or episodically (like viagra or periactin) can relieve the sexual side effects in many patients without disrupting the beneficial actions of the SSRI.

I am sorry you have OCD, it can be crippling, but therapy and medications can often really help, and as you hinted, in some people the treatment can be fairly short. I encourage you to work with a psychiatrist AND and therapist (or a psychiatrist who does therapy) since the combination is more likely to be succesful and to last after you stop the zoloft. Good luck.
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